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Rapid Testing
Test tubes of gold colloid used in rapid tests
TEM micrograph a gold colloid showing 40nm gold particles Gold is the perfect raw material for rapid testing. A rapid test is an inexpensive, disposable, membrane-based technique that provides visual evidence of the presence of an analyte in a liquid sample. Applications for rapid tests include clinical uses (fertility tests, tumor markers, toxicology, allergies), agricultural uses (food safety, plant and crop diseases) and environmental uses (biological and environmental contamination.) Early rapid tests used coloured latex to form the visual signal. However, gold labels were first introduced into membrane-based rapid tests in the late 1980s, because of their greater potential stability and an ever-increasing demand for ultra sensitivity. These labels are based on gold colloids (a suspension of nanometer sized gold particles individually surrounded by a negative charge layer. This charge layer provides the means for the gold particles to repel each other and stay in suspension indefinitely.) Gold is essentially inert and forms almost perfectly spherical particles when properly manufactured. Proteins bind to the surfaces of these gold particles with enormous strength when correctly coupled, thus providing a high degree of long-term stability in both liquid and dry states. If manufacturing processes ensure that gold particles of any accurately defined size can be manufactured reproducibly, there will be minimal batch to batch variation. What's more, different sizes of gold may be used for different applications, thus making it a very flexible raw material for both manufacture and development. Overall, the superior stability, sensitivity and reproducibility of manufacture, make gold a first class raw material component for a wide range of rapid test applications. For more information see the website of BBInternational, a leading supplier of gold colloid used in rapid tests www.bb-international.com Read more about gold colloid and gold nanoparticles in Gold Bulletin |
![]() The blog that crosses the boundaries between research and the industrial application of gold technology Call for papers12 Mar, 2010 Journal of Materials Research has announced a special focus issue for January 2011, featuring new developments in self-assembly and directed assembly of advanced materials. This focus issue will include several invited overview papers, invited feature papers, and original contributions. Papers related to gold nanotechnology will be particularly relevant for this publication, so you should get [...] |